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Preface: I'm running a github clone of Vanilla 2.1a, so if this is the cause of my problem, then I totally understand and I'll shut up about it :)
Enabling the Vanilla Statistics plugin causes the dashboard front page to be displayed again inside of itself—looks like this. I can duplicate the behavior in Firefox, Safari, and Chrome. Is this just a 2.1 incompatibility that will eventually be fixed, or am I doing something wrong?